Internationally, vaccine pricing is relatively opaque, although many low- or lower-middle-income countries belong to international consortiums that jointly procure vaccines.China procures vaccines domestically, and vaccines that require payment from the public (“category 2 vaccines”), have undergone several regulatory changes over the p
We have recently suggested a novel mechanism, autoendocytosis, for the entry of certain microbes into their hosts, with a knob creek apparel key role played by the sphingomyelinase-catalyzed topical conversion of sphingomyelin to ceramide, the differences in the biophysical properties of these two lipids providing the driving force.The only require
Introduction Chronic kidney disease (CKD) is a global-health problem.A significant proportion of referrals to fr9967 nephrologists for CKD management are early and guideline-discordant, which may lead to an excess number of referrals and increased wait-times.Various initiatives have been tested to increase the proportion of guideline-concordant ref
Introduction Late onset muscle soreness, also known as delayed onset muscle soreness, is a painful musculoskeletal condition that may occur 24-48 and up to 72 hours after the completion of unusual physical or high intensity exercise involving eccentric muscle activity.In the field of physical rehabilitation, immersion in cold water is a common inte
Vascularized composite tissue allotransplantation (VCA) offers treatment options of complex functional deficiencies that cannot be repaired with conventional reconstructive methods.VCAs consist of blocks of functional units comprising different tissue types such as skin, bone, muscle, nerves, blood vessels, tendons, ligaments and others, and are th